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SLC2A5 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P22732
Clone Names 100528133
Peptide ID 100528133
Additional Information
Gene ID 6518
Other Names Solute carrier family 2, facilitated glucose transporter member 5, Fructose transporter, Glucose transporter type 5, small intestine, GLUT-5, SLC2A5, GLUT5
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC2A5
Synonyms GLUT5
Function Functions as a fructose transporter that has only low activity with other monosaccharides (PubMed:8333543). Can mediate the uptake of 2-deoxyglucose, but with low efficiency (PubMed:1695905). Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake (By similarity).
Cellular Location Apical cell membrane {ECO:0000250|UniProtKB:Q9WV38}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9WV38}. Cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9WV38}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:P43427}. Note=Localized on the apical membrane of jejunum villi, but also on lateral plasma membranes of the villi. Transport to the cell membrane is dependent on RAB11A {ECO:0000250|UniProtKB:Q9WV38}
Tissue Location Detected in skeletal muscle, and in jejunum brush border membrane and basolateral membrane (at protein level) (PubMed:7619085). Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue
Research Areas
Citations (0)

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SLC2A5 is a cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Inamochi, Y., et al. Biochem. Biophys. Res. Commun. 392(1):16-21(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Barone, S., et al. J. Biol. Chem. 284(8):5056-5066(2009)

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$ 80.00
Cat# BP16142c
Availability: In Stock
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