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Mouse Stradb Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8K4T3
Clone Names 110328113
Additional Information
Gene ID 227154
Other Names STE20-related kinase adapter protein beta, STRAD beta, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog, ILP-interacting protein homolog, Polyploidy-associated protein kinase, Pseudokinase ALS2CR2, Stradb, Als2cr2, Papk, Syradb
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Stradb
Synonyms Als2cr2, Papk, Syradb
Function Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity).
Cellular Location Nucleus. Cytoplasm.
Research Areas
Citations (0)
citation

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Background

Pseudokinase which, in complex with CAB39, binds to and activates STK11. Relocates STK11 from the nucleus to the cytoplasm. Plays an essential role in STK11-mediated G1 cell cycle arrest.

References

Ling, K.H., et al. Genome Biol. 10 (10), R104 (2009) :Barnes, A.P., et al. Cell 129(3):549-563(2007)Nishigaki, K., et al. J. Biol. Chem. 278(15):13520-13530(2003)Welch, C.L., et al. Mamm. Genome 8(8):620-621(1997)Welch, C.L., et al. J. Lipid Res. 37(7):1406-1421(1996)

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$ 277.78
Cat# BP16163b
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