|Other Names||GPI transamidase component PIG-T, Phosphatidylinositol-glycan biosynthesis class T protein, PIGT|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type I membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that is involved inglycosylphosphatidylinositol (GPI)-anchor biosynthesis. TheGPI-anchor is a glycolipid found on many blood cells and serves toanchor proteins to the cell surface. This protein is an essentialcomponent of the multisubunit enzyme, GPI transamidase. GPItransamidase mediates GPI anchoring in the endoplasmic reticulum,by catalyzing the transfer of fully assembled GPI units toproteins. Several transcript variants encoding different isoformshave been found for this gene.
Li, H.L., et al. FEBS Lett. 580(7):1723-1728(2006)Vainauskas, S., et al. J. Biol. Chem. 280(16):16402-16409(2005)Ohishi, K., et al. J. Biol. Chem. 278(16):13959-13967(2003)Eisenhaber, B., et al. Bioessays 25(4):367-385(2003)Vainauskas, S., et al. J. Biol. Chem. 277(34):30535-30542(2002)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.