C9orf46 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9HBL7 |
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Clone Names | 100406236 |
Gene ID | 55848 |
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Other Names | Plasminogen receptor (KT), Plg-R(KT), PLGRKT, C9orf46 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PLGRKT |
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Synonyms | C9orf46 |
Function | Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator- dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metalloproteinase activation, such as of MMP2 and MMP9. |
Cellular Location | Cell membrane; Multi-pass membrane protein Note=Colocalizes on the cell surface with urokinase plasminogen activator surface receptor/PLAUR. |
Tissue Location | Expressed in peripheral blood cells and monocytes. Expressed in adrenal medulla. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The exact function of C9ORF46 remains unknown.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Lamesch, P., et al. Genomics 89(3):307-315(2007)Humphray, S.J., et al. Nature 429(6990):369-374(2004)
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