|Other Names||Plasminogen receptor (KT), Plg-R(KT), PLGRKT, C9orf46|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metallproteinase activation, such as of MMP2 and MMP9.|
|Cellular Location||Cell membrane; Multi-pass membrane protein Note=Colocalizes on the cell surface with urokinase plasminogen activator surface receptor/PLAUR.|
|Tissue Location||Expressed in peripheral blood cells and monocytes. Expressed in adrenal medulla|
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Provided below are standard protocols that you may find useful for product applications.
The exact function of C9ORF46 remains unknown.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Lamesch, P., et al. Genomics 89(3):307-315(2007)Humphray, S.J., et al. Nature 429(6990):369-374(2004)
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