|Other Names||Rho-related GTP-binding protein RhoG, RHOG, ARHG|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Required for the formation of membrane ruffles during macropinocytosis. Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB and ARHGEF26/SGEF, which induces cytoskeleton rearrangements and promotes bacterial entry.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side|
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Provided below are standard protocols that you may find useful for product applications.
ARHG is a member of the RAS superfamily of genes, whichencode GTP-binding proteins that act in the pathway of signaltransduction and play a key role in the regulation of cellularfunctions.
Hiramoto-Yamaki, N., et al. J. Cell Biol. 190(3):461-477(2010)Segat, L., et al. Vaccine 28(10):2201-2206(2010)Landa, I., et al. PLoS Genet. 5 (9), E1000637 (2009) :Roppenser, B., et al. J. Cell. Sci. 122 (PT 5), 696-705 (2009) :van Buul, J.D., et al. J. Cell Biol. 178(7):1279-1293(2007)
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