|Other Names||Immunoglobulin-binding protein 1, B-cell signal transduction molecule alpha 4, Protein alpha-4, CD79a-binding protein 1, Protein phosphatase 2/4/6 regulatory subunit, Renal carcinoma antigen NY-REN-16, IGBP1, IBP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits.|
|Tissue Location||Ubiquitously expressed with highest levels in heart, skeletal muscle and pancreas|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The proliferation and differentiation of B cells isdependent upon a B-cell antigen receptor (BCR) complex. Binding ofantigens to specific B-cell receptors results in a tyrosinephosphorylation reaction through the BCR complex and leads tomultiple signal transduction pathways.
McDonald, W.J., et al. J. Cell. Biochem. 110(5):1123-1129(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Fielhaber, J.A., et al. J. Biol. Chem. 284(36):24341-24353(2009)Chen, G.I., et al. J. Biol. Chem. 283(43):29273-29284(2008)Aranda-Orgilles, B., et al. PLoS ONE 3 (10), E3507 (2008) :
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.