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LIM2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P55344 |
|---|---|
| Clone Names | 101008256 |
| Gene ID | 3982 |
|---|---|
| Other Names | Lens fiber membrane intrinsic protein, MP18, MP19, MP20, LIM2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LIM2 |
|---|---|
| Function | Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis. |
| Cellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Location | Eye lens specific.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
LIM2 is an eye lens-specific protein found atthe junctions of lens fiber cells, where it may contribute to celljunctional organization. It acts as a receptor for calmodulin, andmay play an important role in both lens development andcataractogenesis. Mutations in this gene have been associated withcataract formation.
References
Ponnam, S.P., et al. Mol. Vis. 14, 1204-1208 (2008) :Hsu, H., et al. Sheng Wu Gong Cheng Xue Bao 20(4):507-515(2004)Wistow, G., et al. Mol. Vis. 8, 171-184 (2002) :Wistow, G., et al. Mol. Vis. 8, 185-195 (2002) :Pras, E., et al. Am. J. Hum. Genet. 70(5):1363-1367(2002)
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