MRGPRX3 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96LB0 |
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Clone Names | 100517271 |
Gene ID | 117195 |
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Other Names | Mas-related G-protein coupled receptor member X3, Sensory neuron-specific G-protein coupled receptor 1/2, MRGPRX3, MRGX3, SNSR1, SNSR2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MRGPRX3 |
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Synonyms | MRGX3, SNSR1, SNSR2 |
Function | Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. |
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Provided below are standard protocols that you may find useful for product applications.
Background
MRGPRX3 is a member of the mas-related/sensoryneuron specific subfamily of G protein coupled receptors. Theencoded protein may be involved in sensory neuron regulation and inthe modulation of pain.
References
Burstein, E.S., et al. Br. J. Pharmacol. 147(1):73-82(2006)Kaisho, Y., et al. Biochem. Biophys. Res. Commun. 330(3):653-657(2005)Lembo, P.M., et al. Nat. Neurosci. 5(3):201-209(2002)Dong, X., et al. Cell 106(5):619-632(2001)
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