|Other Names||Homeobox protein Hox-B9, Homeobox protein Hox-25, Homeobox protein Hox-2E, HOXB9, HOX2E|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.|
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Provided below are standard protocols that you may find useful for product applications.
HOXB9 is a member of the Abd-B homeobox family andencodes a protein with a homeobox DNA-binding domain. It isincluded in a cluster of homeobox B genes located on chromosome 17.The encoded nuclear protein functions as a sequence-specifictranscription factor that is involved in cell proliferation anddifferentiation. Increased expression of this gene is associatedwith some cases of leukemia, prostate cancer and lung cancer.
Hayashida, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(3):1100-1105(2010)Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)Rouault, K., et al. Osteoarthr. Cartil. 17(8):1099-1105(2009)Nguyen, D.X., et al. Cell 138(1):51-62(2009)Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
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