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TNFRSF17 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q02223
Clone Names 100528062
Peptide ID 100528062
Additional Information
Gene ID 608
Other Names Tumor necrosis factor receptor superfamily member 17, B-cell maturation protein, CD269, TNFRSF17, BCM, BCMA
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms BCM, BCMA
Function Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Cellular Location Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Note=Perinuclear Golgi-like structures
Tissue Location Expressed in mature B-cells, but not in T- cells or monocytes
Research Areas
Citations (0)

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The protein encoded by this gene is a member of theTNF-receptor superfamily. This receptor is preferentially expressedin mature B lymphocytes, and may be important for B celldevelopment and autoimmune response. This receptor has been shownto specifically bind to the tumor necrosis factor (ligand)superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead toNF-kappaB and MAPK8/JNK activation. This receptor also binds tovarious TRAF family members, and thus may transduce signals forcell survival and proliferation.


Chae, S.C., et al. Mol. Cells 29(1):21-28(2010)Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)Barone, F., et al. Mucosal Immunol 2(6):495-503(2009)Newton-Cheh, C., et al. Nat. Genet. 41(4):399-406(2009)Li, H., et al. PLoS ONE 4 (7), E6410 (2009) :

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$ 80.00
Cat# BP16248c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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