|Other Names||Krueppel-like factor 9, Basic transcription element-binding protein 1, BTE-binding protein 1, GC-box-binding protein 1, Transcription factor BTEB1, KLF9, BTEB, BTEB1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that binds to GC box promoter elements. Selectively activates mRNA synthesis from genes containing tandem repeats of GC boxes but represses genes with a single GC box. Acts as an epidermal circadian transcription factor regulating keratinocyte proliferation (PubMed:22711835).|
|Tissue Location||Epidermis (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a transcription factorthat binds to GC box elements located in the promoter. Binding ofthe encoded protein to a single GC box inhibits mRNA expressionwhile binding to tandemly repeated GC box elements activatestranscription.
Du, H., et al. Biol. Reprod. 83(2):205-211(2010)Pabona, J.M., et al. Endocrinology 151(7):3396-3406(2010)Gamper, I., et al. Exp. Hematol. 37(5):539-548(2009)Kang, L., et al. Pathol. Int. 58(6):334-338(2008)Simmen, F.A., et al. Reprod. Biol. Endocrinol. 6, 41 (2008) :
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