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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   TNFSF18 Antibody (Center) Blocking Peptide   

TNFSF18 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UNG2
Clone Names 100528122
Peptide ID 100528122
Additional Information
Gene ID 8995
Other Names Tumor necrosis factor ligand superfamily member 18, Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, hGITRL, TNFSF18, AITRL, GITRL, TL6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFSF18
Synonyms AITRL, GITRL, TL6
Function Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T- cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation (By similarity).
Cellular Location Cell membrane; Single-pass type II membrane protein
Tissue Location Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells
Research Areas
Citations (0)

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The protein encoded by this gene is a cytokine thatbelongs to the tumor necrosis factor (TNF) ligand family. Thiscytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has beenshown to modulate T lymphocyte survival in peripheral tissues. Thiscytokine is also found to be expressed in endothelial cells, and isthought to be important for interaction between T lymphocytes andendothelial cells.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Han, S., et al. Hum. Immunol. 71(7):727-730(2010)Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)

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$ 80.00
Cat# BP16250c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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