|Other Names||Cyclin-dependent kinase 10, Cell division protein kinase 10, Cdk10|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells).|
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Provided below are standard protocols that you may find useful for product applications.
Cdk10 belongs to the CDK(cyclin-dependent kinase) subfamily of the Ser/Thr protein kinasefamily. The CDK subfamily members are highly similar to the geneproducts of S. cerevisiae cdc28, and S. pombe cdc2, and are knownto be essential for cell cycle progression. The human ortholog hasbeen shown to play a role in cellular proliferation. Multipletranscript variants encoding different isoforms have been found forthis gene. A related pseudogene exists on chromosome 1. [providedby RefSeq].
Bagella, L., et al. J. Cell. Biochem. 99(3):978-985(2006)Grana, X., et al. Oncogene 9(7):2097-2103(1994)
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