|Other Names||Homeobox protein Hox-D1, Homeobox protein Hox-GG, HOXD1, HOX4, HOX4G|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.|
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Provided below are standard protocols that you may find useful for product applications.
HOXD1 is a member of the Antp homeobox family andencodes a protein with a homeobox DNA-binding domain. This nuclearprotein functions as a sequence-specific transcription factor thatis involved in differentiation and limb development. Mutations inthis gene have been associated with severe developmental defects onthe anterior-posterior (a-p) limb axis.
Goode, E.L., et al. Nat. Genet. 42(10):874-879(2010)Ester, A.R., et al. Am. J. Med. Genet. A 149A (12), 2745-2752 (2009) :Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Kosaki, K., et al. Teratology 65(2):50-62(2002)Pitera, J.E., et al. Mech. Dev. 109(2):377-381(2001)
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