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TRAPPC2 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P0DI81
Clone Names 100318016
Additional Information
Gene ID 6399
Other Names Trafficking protein particle complex subunit 2, Sedlin, TRAPPC2, SEDL
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRAPPC2
Synonyms SEDL
Function Prevents transcriptional repression and induction of cell death by ENO1 (By similarity). May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Cellular Location Cytoplasm, perinuclear region. Endoplasmic reticulum-Golgi intermediate compartment. Nucleus. Cytoplasm. Note=Localized in perinuclear granular structures.
Tissue Location Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, fetal cartilage, fibroblasts, placenta and lymphocytes.
Research Areas
Citations (0)
citation

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Background

TRAPPC2 is thought to be part ofa large multi-subunit complex involved in the targeting and fusionof endoplasmic reticulum-to-Golgi transport vesicles with theiracceptor compartment. In addition, the encoded protein can bindc-myc promoter-binding protein 1 and block its transcriptionalrepression capability. Mutations in this gene are a cause ofspondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogeneof this gene is located on chromosome 19, and other pseudogenes arefound on chromosomes 8 and Y.

References

Liu, X., et al. J. Cell. Biochem. 109(6):1129-1133(2010)Jeyabalan, J., et al. PLoS ONE 5 (5), E10646 (2010) :Xia, X.Y., et al. Clin. Chim. Acta 410 (1-2), 39-42 (2009) :Guo, H., et al. J. Genet. 88(1):87-91(2009)Xiong, F., et al. Eur. J. Hum. Genet. 17(4):510-516(2009)

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$ 277.78
Cat# BP16270a
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