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BNC1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q01954
Clone Names 100324038
Peptide ID 100324038
Additional Information
Gene ID 646
Other Names Zinc finger protein basonuclin-1, BNC1, BNC
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BNC1
Synonyms BNC
Function Transcriptional activator (By similarity). Likely specific for squamous epithelium and for the constituent keratinocytes at a stage either prior to or at the very beginning of terminal differentiation (PubMed:8034748). Required for the maintenance of spermatogenesis (By similarity). May also play a role in the differentiation of oocytes and the early development of embryos (By similarity).
Cellular Location Nucleus. Cytoplasm. Nucleus, nucleoplasm. Note=Relocates to the midpiece of the flagellum during late spermiogenesis in spermatids {ECO:0000250|UniProtKB:O35914}
Tissue Location In epidermis, primarily detected in cells of the basal or immediately suprabasal layers (at protein level) (PubMed:16891417). In hair follicles, mainly expressed in the outer root sheath (at protein level) (PubMed:8034748). Expressed in epidermis, testis and foreskin, and to a lower extent in thymus, spleen, mammary glands, placenta, brain and heart (PubMed:9687312).
Research Areas
Citations (0)

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The protein encoded by this gene is a zinc finger proteinpresent in the basal cell layer of the epidermis and in hairfollicles. It is also found in abundance in the germ cells oftestis and ovary. This protein is thought to play a regulatory rolein keratinocyte proliferation and it may also be a regulator forrRNA transcription. This gene seems to have multiple alternativelyspliced transcript variants, but their full-length nature is notknown yet. There seems to be evidence of multiple polyadenylationsites for this gene.


Vanhoutteghem, A., et al. Proc. Natl. Acad. Sci. U.S.A. 103(33):12423-12428(2006)Iuchi, S., et al. Exp. Dermatol. 9(3):178-184(2000)Tang, W., et al. Gene 237(1):35-44(1999)Tseng, H., et al. J. Cell. Sci. 112 PT 18, 3039-3047 (1999) :Iuchi, S., et al. Proc. Natl. Acad. Sci. U.S.A. 96(17):9628-9632(1999)

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$ 80.00
Cat# BP16281a
Availability: In Stock
Bulk Size
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