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MKKS Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NPJ1
Clone Names 100318130
Peptide ID 100318130
Additional Information
Gene ID 8195
Other Names McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin, Bardet-Biedl syndrome 6 protein, MKKS, BBS6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MKKS
Synonyms BBS6
Function Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis.
Cellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol. Note=The majority of the protein resides within the pericentriolar material (PCM), a proteinaceous tube surrounding centrioles. During interphase, the protein is confined to the lateral surfaces of the PCM but during mitosis it relocalizes throughout the PCM and is found at the intercellular bridge. The MKSS protein is highly mobile and rapidly shuttles between the cytosol and centrosome
Tissue Location Widely expressed in adult and fetal tissues.
Research Areas
Citations (0)

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Background

MKKS is a protein with sequence similarity tothe chaperonin family. The encoded protein may have a role inprotein processing in limb, cardiac and reproductive systemdevelopment. Mutations in this gene have been observed in patientswith Bardet-Biedl syndrome type 6 and McKusick-Kaufman syndrome.Two transcript variants encoding the same protein have beenidentified for this gene.

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Billingsley, G., et al. J. Med. Genet. 47(7):453-463(2010)Corpeleijn, E., et al. Obesity (Silver Spring) 18(7):1369-1377(2010)Mukherjee, K., et al. BMC Evol. Biol. 10, 64 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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$ 80.00
Cat# BP16289b
Size:
Quantity:
(40 western blots)
Availability: In Stock
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Seasonal Special on Bulk Order
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