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PAP2D Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q32ZL2 |
|---|---|
| Clone Names | 100422044 |
| Gene ID | 163404 |
|---|---|
| Other Names | Lipid phosphate phosphatase-related protein type 5, 313-, Phosphatidic acid phosphatase 2d, Plasticity-related gene 5 protein, PRG-5, LPPR5, PAP2D |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PLPPR5 (HGNC:31703) |
|---|---|
| Function | Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory-mediated axonal retraction. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q8BJ52}; Multi-pass membrane protein |
| Tissue Location | Isoform 1 is expressed in brain, lung, kidney and colon. Isoform 2 is expressed in placenta, skeletal muscle and kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
PAP2D is a type 2 member of thephosphatidic acid phosphatase (PAP) family. All type 2 members ofthis protein family contain 6 transmembrane regions, and aconsensus N-glycosylation site. PAPs convert phosphatidic acid todiacylglycerol, and function in de novo synthesis of glycerolipidsas well as in receptor-activated signal transduction mediated byphospholipase D. Alternate transcriptional splice variants,encoding different isoforms, have been characterized. [provided byRefSeq].
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Broggini, T., et al. Mol. Biol. Cell 21(4):521-537(2010)Sun, L., et al. Mol. Cell. Biochem. 272 (1-2), 91-96 (2005) :
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