TMEM45B Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96B21 |
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Other Accession | NP_620143.1 |
Clone Names | 100422125 |
Gene ID | 120224 |
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Other Names | Transmembrane protein 45B, TMEM45B |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TMEM45B |
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Function | Plays a role in innate immunity (PubMed:35938871). Mechanistically, promotes alphaviruses RNA degradation by interacting with the viral polymerase nsP4 and the mRNA-capping enzyme nsP1 and thereby interfering with the interaction between viral RNA and nsP1.(PubMed:35938871). |
Cellular Location | Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
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