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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   RBBP7 Antibody (Center) Blocking Peptide   

RBBP7 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q16576
Clone Names 100427214
Peptide ID 100427214
Additional Information
Gene ID 5931
Other Names Histone-binding protein RBBP7, Histone acetyltransferase type B subunit 2, Nucleosome-remodeling factor subunit RBAP46, Retinoblastoma-binding protein 7, RBBP-7, Retinoblastoma-binding protein p46, RBBP7, RBAP46
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RBBP7
Synonyms RBAP46
Function Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
Cellular Location Nucleus.
Research Areas
Citations (0)

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This protein is a ubiquitously expressed nuclear proteinand belongs to a highly conserved subfamily of WD-repeat proteins.It is found among several proteins that binds directly toretinoblastoma protein, which regulates cell proliferation. Theencoded protein is found in many histone deacetylase complexes,including mSin3 co-repressor complex. It is also present in proteincomplexes involved in chromatin assembly. This protein can interactwith BRCA1 tumor-suppressor gene and may have a role in theregulation of cell proliferation and differentiation. Twotranscript variants encoding different isoforms have been found forthis gene.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Saade, E., et al. Proteomics 9(21):4934-4943(2009)Wang, C.L., et al. J. Proteome Res. 8(10):4428-4440(2009)Li, R., et al. EMBO J. 28(18):2763-2776(2009)

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$ 80.00
Cat# BP16321c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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