|Other Names||GTP-binding protein Rhes, Ras homolog enriched in striatum, Tumor endothelial marker 2, RASD2, TEM2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination.|
|Cellular Location||Cell membrane; Lipid-anchor|
|Tissue Location||Pancreatic endocrine cells (islets of Langerhans).|
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Provided below are standard protocols that you may find useful for product applications.
RASD2 is a Ras-related protein that enriched instriatum. The product of this gene binds to GTP and possessesintrinsic GTPase activity. The gene belongs to the Ras superfamilyof small GTPases. The exact function of this gene is unknown, butmost striatum-specific mRNAs characterized to date encodecomponents of signal transduction cascades.
Hill, C., et al. Cell. Physiol. Biochem. 23 (1-3), 1-8 (2009) :Liu, Y.L., et al. Biol. Psychiatry 64(9):789-796(2008)Thapliyal, A., et al. Am. J. Physiol., Cell Physiol. 295 (5), C1417-C1426 (2008) :Agretti, P., et al. J. Endocrinol. Invest. 30(4):279-284(2007)Taylor, J.P., et al. Biochem. Biophys. Res. Commun. 349(2):809-815(2006)
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