|Other Names||Zinc transporter ZIP6, Estrogen-regulated protein LIV-1, Solute carrier family 39 member 6, Zrt- and Irt-like protein 6, ZIP-6, SLC39A6, LIV1, ZIP6|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May act as a zinc-influx transporter.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma|
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Provided below are standard protocols that you may find useful for product applications.
Zinc is an essential cofactor for hundreds of enzymes. Itis involved in protein, nucleic acid, carbohydrate, and lipidmetabolism, as well as in the control of gene transcription,growth, development, and differentiation. SLC39A6 belongs to asubfamily of proteins that show structural characteristics of zinctransporters (Taylor and Nicholson, 2003 [PubMed12659941]).
Lopez, V., et al. Exp. Cell Res. 316(3):366-375(2010)Ma, X., et al. Mol. Cancer Ther. 8(11):3108-3116(2009)Unno, J., et al. Int. J. Oncol. 35(4):813-821(2009)French, D., et al. Blood 113(19):4512-4520(2009)Shen, H., et al. Mol. Biol. Rep. 36(4):653-659(2009)
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