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Erythropoietin Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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  • CITATIONS
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Product Information
Primary Accession P01588
Clone Names 80808091
Additional Information
Gene ID 2056
Other Names Erythropoietin, Epoetin, EPO
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EPO
Function Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
Cellular Location Secreted.
Tissue Location Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals
Research Areas
Citations (0)
citation

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Background

EPO is a member of the EPO/TPO family and encodes asecreted, glycosylated cytokine composed of four alpha helicalbundles. The protein is found in the plasma and regulates red cellproduction by promoting erythroid differentiation and initiatinghemoglobin synthesis. This protein also has neuroprotectiveactivity against a variety of potential brain injuries andantiapoptotic functions in several tissue types. [provided byRefSeq].

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Kristensen, P.L., et al. Eur. J. Endocrinol. 163(3):391-398(2010)Kim, M.H., et al. Mol. Biol. (Mosk.) 44(4):656-663(2010)Carraway, M.S., et al. Circ. Res. 106(11):1722-1730(2010)Shi, Z., et al. Mol. Cancer Res. 8(4):615-626(2010)

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$ 277.78
Cat# BP16337a
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