|Other Names||KRAB domain-containing protein 4, KRAB box domain-containing protein 4, KRBOX4, ZNF673|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Expressed in brain, ovary, testis, prostate, tonsil, heart, bone marrow, colon, breast and kidney|
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ZNF673 belongs to the krueppel C2H2-type zinc-finger protein family. ZNF673 may be involved in transcriptional regulation. Defects in ZNF673 may be the cause of mental retardation X-linked type 92 (MRX92). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
Lugtenberg, D., et al. Am. J. Hum. Genet. 78(2):265-278(2006)Ross, M.T., et al. Nature 434(7031):325-337(2005)Thiselton, D.L., et al. Genomics 79(4):560-572(2002)
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