EME2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | A4GXA9 |
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Clone Names | 91230094 |
Gene ID | 197342 |
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Other Names | Probable crossover junction endonuclease EME2, 3122-, EME2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | EME2 |
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Function | Interacts with MUS81 to form a DNA structure-specific endonuclease which cleaves substrates such as 3'-flap structures. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
EME2 forms a heterodimer with MUS81 (MIM 606591) thatfunctions as an XPF (MIM 278760)-type flap/fork endonuclease in DNArepair (Ciccia et al., 2007 [PubMed 17289582]).
References
Ciccia, A., et al. Mol. Cell 25(3):331-343(2007)Ciccia, A., et al. J. Biol. Chem. 278(27):25172-25178(2003)Daniels, R.J., et al. Hum. Mol. Genet. 10(4):339-352(2001)
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