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EME2 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession A4GXA9
Clone Names 91230094
Peptide ID 91230094
Additional Information
Gene ID 197342
Other Names Probable crossover junction endonuclease EME2, 3122-, EME2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EME2
Function Interacts with MUS81 to form a DNA structure-specific endonuclease which cleaves substrates such as 3'-flap structures.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

EME2 forms a heterodimer with MUS81 (MIM 606591) thatfunctions as an XPF (MIM 278760)-type flap/fork endonuclease in DNArepair (Ciccia et al., 2007 [PubMed 17289582]).

References

Ciccia, A., et al. Mol. Cell 25(3):331-343(2007)Ciccia, A., et al. J. Biol. Chem. 278(27):25172-25178(2003)Daniels, R.J., et al. Hum. Mol. Genet. 10(4):339-352(2001)

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$ 80.00
Cat# BP16348b
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