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ISL1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P61371
Clone Names 100525296
Peptide ID 100525296
Additional Information
Gene ID 3670
Other Names Insulin gene enhancer protein ISL-1, Islet-1, ISL1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ISL1
Function Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity).
Cellular Location Nucleus.
Tissue Location Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain
Research Areas
Citations (0)

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ISL1 is a member of the LIM/homeodomain familyof transcription factors. The encoded protein binds to the enhancerregion of the insulin gene, among others, and may play an importantrole in regulating insulin gene expression. The encoded protein iscentral to the development of pancreatic cell lineages and may alsobe required for motor neuron generation. Mutations in this genehave been associated with maturity-onset diabetes of the young.


De Luca, A., et al. Clin. Genet. (2010) In press :Davis, O.S., et al. Behav. Genet. (2010) In press :Genead, R., et al. Stem Cell Res 4(1):69-76(2010)Stevens, K.N., et al. PLoS ONE 5 (5), E10855 (2010) :Zhang, H., et al. J. Mol. Biol. 392(3):566-577(2009)

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$ 80.00
Cat# BP16352c
(40 western blots)
Availability: In Stock
Bulk Size
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