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SLC30A2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BRI3 |
|---|---|
| Clone Names | 100416082 |
| Gene ID | 7780 |
|---|---|
| Other Names | Zinc transporter 2, ZnT-2, Solute carrier family 30 member 2, SLC30A2, ZNT2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SLC30A2 (HGNC:11013) |
|---|---|
| Function | [Isoform 1]: Electroneutral proton-coupled antiporter concentrating zinc ions into a variety of intracellular organelles including endosomes, zymogen granules and mitochondria. Thereby, plays a crucial role in cellular zinc homeostasis to confer upon cells protection against its potential cytotoxicity (PubMed:21289295, PubMed:25808614, PubMed:25657003, PubMed:30893306, PubMed:17065149, PubMed:22733820). Regulates the zinc concentration of milk, through the transport of zinc ions into secretory vesicles of mammary cells (PubMed:19496757). By concentrating zinc ions into lysosomes participates to lysosomal-mediated cell death during early mammary gland involution (PubMed:25808614). |
| Cellular Location | [Isoform 1]: Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein. Zymogen granule membrane {ECO:0000250|UniProtKB:Q2HJ10}; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein. Note=Localization to lysosomes is induced by TNF-alpha |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Lopez, V., et al. Biochem. J. 422(1):43-52(2009)Shen, M., et al. Environ. Mol. Mutagen. 50(4):285-290(2009)Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)Overbeck, S., et al. J. Leukoc. Biol. 83(2):368-380(2008)Falcon-Perez, J.M., et al. Exp. Cell Res. 313(7):1473-1483(2007)
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