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HTR7 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P34969
Clone Names 100430127
Additional Information
Gene ID 3363
Other Names 5-hydroxytryptamine receptor 7, 5-HT-7, 5-HT7, 5-HT-X, Serotonin receptor 7, HTR7
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HTR7
Function This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels Isoform D is a minor isoform in terms of expression
Research Areas
Citations (0)
citation

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Background

The neurotransmitter, serotonin, is thought to play a rolein various cognitive and behavioral functions. The serotoninreceptor encoded by this gene belongs to the superfamily of Gprotein-coupled receptors and the gene is a candidate locus forinvolvement in autistic disorder and other neuropsychiatricdisorders. Three splice variants have been identified which encodeproteins that differ in the length of their carboxy terminal ends.

References

Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :Corominas, R., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (1), 177-184 (2010) :Wei, Z., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry 33(3):547-551(2009)Iceta, R., et al. J. Physiol. Pharmacol. 60(1):157-164(2009)

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$ 277.78
Cat# BP16398b
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