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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   GUCA2B Antibody (C-term) Blocking Peptide   

GUCA2B Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q16661
Clone Names 100528159
Peptide ID 100528159
Additional Information
Gene ID 2981
Other Names Guanylate cyclase activator 2B, Guanylate cyclase C-activating peptide 2, Guanylate cyclase C-activating peptide II, GCAP-II, Uroguanylin, UGN, GUCA2B
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.
Cellular Location Secreted.
Tissue Location Stomach and intestine.
Research Areas
Citations (0)

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Uroguanylin and guanylin (GUCA2A; MIM 139392), peptidehomologs of the bacterial heat-stable enterotoxins (e.g., the E.coli ST toxin; STa), are endogenous activators of the guanylatecyclase-2C receptor (GUCY2C; MIM 601330), which synthesizes cyclicGMP (cGMP), a key component of several intracellular signaltransduction pathways.


Yoshikawa, Y., et al. Hypertens. Res. 30(9):789-796(2007)Guo, H.F., et al. Zhonghua Xin Xue Guan Bing Za Zhi 35(3):233-236(2007)Sindic, A., et al. Kidney Int. 67(4):1420-1427(2005)Maake, C., et al. Histochem. Cell Biol. 119(1):69-76(2003)Sindice, A., et al. J. Biol. Chem. 277(20):17758-17764(2002)

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$ 80.00
Cat# BP16404b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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