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KIF18A Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8NI77 |
|---|---|
| Clone Names | 100528228 |
| Gene ID | 81930 |
|---|---|
| Other Names | Kinesin-like protein KIF18A, Marrow stromal KIF18A, MS-KIF18A, KIF18A |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | KIF18A |
|---|---|
| Function | Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression. |
| Cellular Location | Cell projection, ruffle. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome |
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Provided below are standard protocols that you may find useful for product applications.
Background
KIF18A is a member of the kinesin superfamily ofmicrotubule-associated molecular motors (see MIM 148760) that usehydrolysis of ATP to produce force and movement along microtubules(Luboshits and Benayahu, 2005 [PubMed 15878648]).[supplied byOMIM].
References
Zhang, C., et al. Carcinogenesis 31(9):1676-1684(2010)Du, Y., et al. Curr. Biol. 20(4):374-380(2010)Huang, Y., et al. Cell Cycle 8(16):2643-2649(2009)Zusev, M., et al. J. Cell. Physiol. 217(3):618-625(2008)Stumpff, J., et al. Dev. Cell 14(2):252-262(2008)
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