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MYT1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q01538 |
|---|---|
| Clone Names | 100528238 |
| Gene ID | 4661 |
|---|---|
| Other Names | Myelin transcription factor 1, MyT1, Myelin transcription factor I, MyTI, PLPB1, Proteolipid protein-binding protein, MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MYT1 |
|---|---|
| Synonyms | KIAA0835, KIAA1050, MTF1, MYTI, PLPB1 |
| Function | Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription. |
| Cellular Location | Nucleus. |
| Tissue Location | Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
MYT1 is a member of a familyof neural specific, zinc finger-containing DNA-binding proteins.The protein binds to the promoter regions of proteolipid proteinsof the central nervous system and plays a role in the developingnervous system.
References
Choi, H.S., et al. Mol. Cell. Biol. 29(8):2168-2180(2009)Vega, A., et al. Gynecol. Oncol. 112(1):210-214(2009)Vana, A.C., et al. Glia 55(7):687-697(2007)Nielsen, J.A., et al. Mol. Cell. Neurosci. 25(1):111-123(2004)Nakajima, H., et al. J. Biol. Chem. 278(28):25277-25280(2003)
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