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RGS8 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P57771
Clone Names 100528272
Peptide ID 100528272
Additional Information
Gene ID 85397
Other Names Regulator of G-protein signaling 8, RGS8, RGS8
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RGS8
Function Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Preferentially binds to G(o)-alpha and G(i)-alpha-3 (By similarity).
Research Areas
Citations (0)

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Background

RGS8 is a member of the regulator of G proteinsignaling (RGS) family and encodes a protein with a single RGSdomain. Regulator of G protein signaling (RGS) proteins areregulatory and structural components of G protein-coupled receptorcomplexes. They accelerate transit through the cycle of GTP bindingand hydrolysis to GDP, thereby terminating signal transduction, butparadoxically, also accelerate receptor-stimulated activation.

References

Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Fujii, S., et al. Biochem. Biophys. Res. Commun. 377(1):200-204(2008)Campbell, D.B., et al. Schizophr. Res. 101 (1-3), 67-75 (2008) :Lamesch, P., et al. Genomics 89(3):307-315(2007)

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$ 80.00
Cat# BP16415a
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