|Other Names||Metabotropic glutamate receptor 8, mGluR8, GRM8, GPRC1H, MGLUR8|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP1641a was selected from the C-term region of human GRPRC1H . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Malherbe, P., et al., Brain Res. Mol. Brain Res. 67(2):201-210 (1999).Scherer, S.W., et al., Genomics 44(2):232-236 (1997).Wu, S., et al., Brain Res. Mol. Brain Res. 53 (1-2), 88-97 (1998).
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