|Other Names||Ribose-phosphate pyrophosphokinase 2, PPRibP, Phosphoribosyl pyrophosphate synthase II, PRS-II, PRPS2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.|
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Provided below are standard protocols that you may find useful for product applications.
PRPS2 is a phosphoribosyl pyrophosphatesynthetase that plays a central role in the synthesis of purinesand pyrimidines. The encoded protein catalyzes the synthesis of5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate.Alternate splicing results in multiple transcript variants.
Mannava, S., et al. Cell Cycle 7(15):2392-2400(2008)Tatibana, M., et al. Adv. Enzyme Regul. 35, 229-249 (1995) :Dawson, S.J., et al. J. Infect. 24(3):317-320(1992)Ishizuka, T., et al. Biochim. Biophys. Acta 1130(2):139-148(1992)Becker, M.A., et al. Genomics 8(3):555-561(1990)
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