|Other Names||Inositol hexakisphosphate kinase 1, InsP6 kinase 1, Inositol hexaphosphate kinase 1, IP6K1, IHPK1, KIAA0263|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.|
|Cellular Location||Cytoplasm. Nucleus|
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Provided below are standard protocols that you may find useful for product applications.
IP6K1 is a protein that belongs to the inositolphosphokinase (IPK) family. This protein is likely responsible forthe conversion of inositol hexakisphosphate (InsP6) todiphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may alsoconvert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.Alternative splicing occurs for this gene; however, the full-lengthnature of all transcript variants has not yet been described.
Morgan, A.R., et al. Hum. Immunol. 71(6):602-609(2010)Padmanabhan, U., et al. J. Biol. Chem. 284(16):10571-10582(2009)Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)Kamimura, J., et al. J. Hum. Genet. 49(7):360-365(2004)Saiardi, A., et al. J. Biol. Chem. 276(42):39179-39185(2001)
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