|Other Names||Scaffold attachment factor B2, SAF-B2, SAFB2, KIAA0138|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.|
|Cellular Location||Cytoplasm. Nucleus.|
|Tissue Location||Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines|
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Provided below are standard protocols that you may find useful for product applications.
SAFB2 binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.
Hammerich-Hille, S., et al. Breast Cancer Res. Treat. 121(2):503-509(2010)Hammerich-Hille, S., et al. J. Biol. Chem. 285(6):3608-3616(2010)Tsianou, D., et al. FEBS J. 276(18):5212-5227(2009)Bergman, A., et al. BMC Med. Genet. 9, 108 (2008) :Olsen, J.V., et al. Cell 127(3):635-648(2006)
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