|Other Names||snRNA-activating protein complex subunit 2, SNAPc subunit 2, Proximal sequence element-binding transcription factor subunit delta, PSE-binding factor subunit delta, PTF subunit delta, Small nuclear RNA-activating complex polypeptide 2, snRNA-activating protein complex 45 kDa subunit, SNAPc 45 kDa subunit, SNAPC2, SNAP45|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.|
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Provided below are standard protocols that you may find useful for product applications.
SNAPC2 is a subunit of the snRNA-activatingprotein complex which is associated with the TATA box-bindingprotein. The encoded protein is necessary for RNA polymerase II andIII dependent small-nuclear RNA gene transcription. Alternativesplicing results in multiple transcript variants. [provided byRefSeq].
Shanmugam, M., et al. J. Biol. Chem. 283(21):14845-14856(2008)Emran, F., et al. Gene 377, 96-108 (2006) :Hinkley, C.S., et al. J. Biol. Chem. 278(20):18649-18657(2003)Acierno, J.S. Jr., et al. Genomics 73(2):203-210(2001)Ma, B., et al. J. Biol. Chem. 276(7):5027-5035(2001)
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