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SNAPC2 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q13487
Clone Names 100603011
Peptide ID 100603011
Additional Information
Other Names snRNA-activating protein complex subunit 2, SNAPc subunit 2, Proximal sequence element-binding transcription factor subunit delta, PSE-binding factor subunit delta, PTF subunit delta, Small nuclear RNA-activating complex polypeptide 2, snRNA-activating protein complex 45 kDa subunit, SNAPc 45 kDa subunit, SNAPC2, SNAP45
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SNAP45
Function Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Cellular Location Nucleus. EMBL; U44898; AAB06230.1; -; mRNA EMBL; U44755; AAC50359.1; -; mRNA EMBL; AK314878; BAG37393.1; -; mRNA EMBL; CH471139; EAW68957.1; -; Genomic_DNA EMBL; CH471139; EAW68958.1; -; Genomic_DNA EMBL; BC011868; AAH11868.1; -; mRNA CCDS; CCDS12190.1; - PIR; JC6082; JC6082 RefSeq; NP_003074.1; NM_003083.3 UniGene; Hs.631860; - ProteinModelPortal; Q13487; - SMR; Q13487; - BioGrid; 112502; 5 DIP; DIP-505N; - IntAct; Q13487; 1 STRING; 9606.ENSP00000221573; - iPTMnet; Q13487; - PhosphoSitePlus; Q13487; - BioMuta; SNAPC2; - DMDM; 8134714; - EPD; Q13487; - MaxQB; Q13487; - PaxDb; Q13487; - PeptideAtlas; Q13487; - PRIDE; Q13487; - DNASU; 6618; - Ensembl; ENST00000221573; ENSP00000221573; ENSG00000104976 GeneID; 6618; - KEGG; hsa:6618; - UCSC; uc002miw.3; human CTD; 6618; - GeneCards; SNAPC2; - HGNC; HGNC:11135; SNAPC2 HPA; HPA049843; - MIM; 605076; gene neXtProt; NX_Q13487; - OpenTargets; ENSG00000104976; - PharmGKB; PA35983; - eggNOG; ENOG410IX3I; Eukaryota eggNOG; ENOG410YPM6; LUCA GeneTree; ENSGT00390000017407; - HOGENOM; HOG000132929; - HOVERGEN; HBG079198; - InParanoid; Q13487; - KO; K15209; - OMA; VEHMTET; - OrthoDB; EOG091G0O5J; - PhylomeDB; Q13487; - TreeFam; TF336993; - BioCyc; ZFISH:ENSG00000104976-MONOMER; - Reactome; R-HSA-6807505; RNA polymerase II transcribes snRNA genes Reactome; R-HSA-749476; RNA Polymerase III Abortive And Retractive Initiation Reactome; R-HSA-76071; RNA Polymerase III Transcription Initiation From Type 3 Promoter GeneWiki; SNAPC2; - GenomeRNAi; 6618; - PRO; PR:Q13487; - Proteomes; UP000005640; Chromosome 19 Bgee; ENSG00000104976; - CleanEx; HS_SNAPC2; - ExpressionAtlas; Q13487; baseline and differential Genevisible; Q13487; HS GO; GO:0005737; C:cytoplasm; IDA:HPA GO; GO:0005654; C:nucleoplasm; TAS:Reactome GO; GO:0005634; C:nucleus; IDA:HPA GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; TAS:ProtInc GO; GO:0009301; P:snRNA transcription; TAS:ProtInc GO; GO:0042795; P:snRNA transcription from RNA polymerase II promoter; TAS:Reactome GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:ProtInc InterPro; IPR021281; SnAPC_su2-like Pfam; PF11035; SnAPC_2_like; 1 1: Evidence at protein level; Complete proteome; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation CHAIN 1 334 snRNA-activating protein complex subunit 2 /FTId=PRO_0000072020 VARIANT 118 118 L -> V (in dbSNP:rs475002) {ECO:0000269|PubMed:14702039, ECO:0000269|Ref.4} /FTId=VAR_011806 SEQUENCE 334 AA; 35556 MW; 441894AF6E1F4083 CRC64; MKPPPRRRAA PARYLGEVTG PATWSAREKR QLVRLLQARQ GQPEPDATEL ARELRGRSEA EIRVFLQQLK GRVAREAIQK VHPGGLQGPR RREAQPPAPI EVWTDLAEKI TGPLEEALAV AFSQVLTIAA TEPVTLLHSK PPKPTQARGK PLLLSAPGGQ EDPAPEIPSS APAAPSSAPR TPDPAPEKPS ESSAGPSTEE DFAVDFEKIY KYLSSVSRSG RSPELSAAES AVVLDLLMSL PEELPLLPCT ALVEHMTETY LRLTAPQPIP AGGSLGPAAE GDGAGSKAPE ETPPATEKAE HSELKSPWQA AGICPLNPFL VPLELLGRAA TPAR
Research Areas
Citations (0)

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SNAPC2 is a subunit of the snRNA-activatingprotein complex which is associated with the TATA box-bindingprotein. The encoded protein is necessary for RNA polymerase II andIII dependent small-nuclear RNA gene transcription. Alternativesplicing results in multiple transcript variants. [provided byRefSeq].


Shanmugam, M., et al. J. Biol. Chem. 283(21):14845-14856(2008)Emran, F., et al. Gene 377, 96-108 (2006) :Hinkley, C.S., et al. J. Biol. Chem. 278(20):18649-18657(2003)Acierno, J.S. Jr., et al. Genomics 73(2):203-210(2001)Ma, B., et al. J. Biol. Chem. 276(7):5027-5035(2001)

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$ 80.00
Cat# BP16427b
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