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ZBTB32 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y2Y4 |
|---|---|
| Clone Names | 100603071 |
| Gene ID | 27033 |
|---|---|
| Other Names | Zinc finger and BTB domain-containing protein 32, FANCC-interacting protein, Fanconi anemia zinc finger protein, Testis zinc finger protein, Zinc finger protein 538, ZBTB32, FAZF, TZFP, ZNF538 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ZBTB32 |
|---|---|
| Synonyms | FAZF, TZFP, ZNF538 |
| Function | DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells (By similarity). |
| Cellular Location | Nucleus. Note=Located in nuclear speckles |
| Tissue Location | Predominantly expressed in testis. Some isoforms are ubiquitously expressed. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZBTB32 is a DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T cells (By similarity).
References
Stogios, P.J., et al. J. Mol. Biol. 400(5):983-997(2010)Kaufmann, S., et al. J. Gen. Virol. 91 (PT 6), 1494-1502 (2010) :Xin, X., et al. Genome Res. 19(7):1262-1269(2009)Cohn, M.A., et al. Mol. Cell 28(5):786-797(2007)Ikeda, R., et al. J. Cell. Biochem. 101(1):147-154(2007)
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