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TAPBPL Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BX59
Clone Names 100603096
Peptide ID 100603096
Additional Information
Gene ID 55080
Other Names Tapasin-related protein, TAPASIN-R, TAP-binding protein-like, TAP-binding protein-related protein, TAPBP-R, Tapasin-like, TAPBPL
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2- microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC). Expression seems to slow down and down-regulate MHC class I surface expression.
Cellular Location Cell membrane; Single-pass type I membrane protein Endoplasmic reticulum membrane; Single-pass type I membrane protein Microsome membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Mainly found in endoplasmic reticulum but a minority is found on the cell surface (PubMed:11920573)
Research Areas
Citations (0)

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Tapasin, or TAPBP (MIM 601962), is a member of thevariable-constant Ig superfamily that links majorhistocompatibility complex (MHC) class I molecules to thetransporter associated with antigen processing (TAP; see MIM170260) in the endoplasmic reticulum (ER). The TAPBP gene islocated near the MHC complex on chromosome 6p21.3. TAPBPL is amember of the Ig superfamily that is localized on chromosome12p13.3, a region somewhat paralogous to the MHC.[supplied byOMIM].


Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)Lee, J.H., et al. Neurogenetics 9(2):127-138(2008)Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)Teng, M.S., et al. Eur. J. Immunol. 32(4):1059-1068(2002)

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$ 80.00
Cat# BP16431a
Availability: In Stock
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