ARMCX1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9P291 |
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Clone Names | 100603186 |
Gene ID | 51309 |
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Other Names | Armadillo repeat-containing X-linked protein 1, ARM protein lost in epithelial cancers on chromosome X 1, Protein ALEX1, ARMCX1, ALEX1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ARMCX1 |
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Synonyms | ALEX1 |
Function | Regulates mitochondrial transport during axon regeneration. Increases the proportion of motile mitochondria by recruiting stationary mitochondria into the motile pool. Enhances mitochondria movement and neurite growth in both adult axons and embryonic neurons. Promotes neuronal survival and axon regeneration after nerve injury. May link mitochondria to the Trak1-kinesin motor complex via its interaction with MIRO1. |
Cellular Location | Mitochondrion {ECO:0000250|UniProtKB:Q9CX83}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q9CX83}; Single- pass membrane protein |
Tissue Location | Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carcinomas. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ARMCX1 is a member of the ALEX family of proteinsand may play a role in tumor suppression. The encoded proteincontains a potential N-terminal transmembrane domain and twoArmadillo (arm) repeats. Other proteins containing the arm repeatare involved in development, maintenance of tissue integrity, andtumorigenesis. This gene is closely localized with other familymembers, including ALEX2 and ALEX3, on the X chromosome. [providedby RefSeq].
References
Iseki, H., et al. Cancer Sci. 101(6):1361-1366(2010)Ross, M.T., et al. Nature 434(7031):325-337(2005)Kurochkin, I.V., et al. Biochem. Biophys. Res. Commun. 280(1):340-347(2001)
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