|Other Names||Galanin receptor type 3, GAL3-R, GALR-3, GALR3, GALNR3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for the hormone galanin (PubMed:25691535). Receptor for the hormone spexin-1 (PubMed:24517231).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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The neuropeptide galanin modulates a variety ofphysiologic processes including cognition/memory, sensory/painprocessing, hormone secretion, and feeding behavior. The humangalanin receptors are G protein-coupled receptors that functionallycouple to their intracellular effector through distinct signalingpathways. GALR3 is found in many tissues and may be expressed as1.4-, 2.4-, and 5-kb transcripts
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Saus, E., et al. J Psychiatr Res 44(14):971-978(2010)Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :Belfer, I., et al. Genes Brain Behav. 6(5):473-481(2007)Berger, A., et al. Neuroendocrinology 75(2):130-138(2002)
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