|Other Names||Mesoderm posterior protein 1, Mesp1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.|
|Tissue Location||No expression was detected in adult tissues except the testis. Expression in the testis was regulated developmentally; expressed 2 weeks after birth, and increases, reaching the full expression level in mature testes|
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Mesp1 is a ranscription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.
Yu, S., et al. Dev. Biol. 347(1):92-108(2010)Li, P., et al. Dev. Cell 18(3):480-485(2010)Powers, S.E., et al. Development 137(2):249-259(2010)Randall, V., et al. J. Clin. Invest. 119(11):3301-3310(2009)Dominguez-Frutos, E., et al. Mech. Dev. 126(10):873-881(2009)
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