CNTROB Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8N137 |
---|---|
Clone Names | 100525325 |
Gene ID | 116840 |
---|---|
Other Names | Centrobin, Centrosomal BRCA2-interacting protein, LYST-interacting protein 8, CNTROB, LIP8 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CNTROB |
---|---|
Synonyms | LIP8 |
Function | Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis. |
Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=Centriole-associated, asymmetrically localizes to the daughter centriole |
Tissue Location | Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
CNTROB is a centrosomal protein that interacts with BRCA2(MIM 600185) and is required for centriole duplication andcytokinesis (Zou et al., 2005 [PubMed 16275750]).[supplied byOMIM].
References
Lee, J., et al. J. Biol. Chem. 285(33):25476-25484(2010)Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :Jeffery, J.M., et al. Oncogene 29(18):2649-2658(2010)Song, L., et al. Cell. Signal. 22(5):857-864(2010)Jeong, Y., et al. J. Cell. Sci. 120 (PT 12), 2106-2116 (2007) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.