CXXC1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9P0U4 |
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Clone Names | 100528217 |
Gene ID | 30827 |
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Other Names | CXXC-type zinc finger protein 1, CpG-binding protein, PHD finger and CXXC domain-containing protein 1, CXXC1, CFP1, CGBP, PCCX1, PHF18 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CXXC1 |
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Synonyms | CFP1, CGBP, PCCX1, PHF18 |
Function | Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. |
Cellular Location | Nucleus speckle. Nucleus {ECO:0000250|UniProtKB:Q9CWW7} Note=Associated with euchromatin. During mitosis, excluded from condensed chromosomes |
Tissue Location | Ubiquitous. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Proteins that contain a CXXC motif within theirDNA-binding domain, such as CXXC1, recognize CpG sequences andregulate gene expression (Carlone and Skalnik, 2001 [PubMed11604496]).
References
Crowther-Swanepoel, D., et al. Nat. Genet. 42(2):132-136(2010)Tate, C.M., et al. Mol. Cell. Biol. 29(14):3817-3831(2009)Butler, J.S., et al. DNA Cell Biol. 27(10):533-543(2008)Ansari, K.I., et al. Biochim. Biophys. Acta 1779(1):66-73(2008)Lee, J.H., et al. Mol. Cell. Biol. 28(2):609-618(2008)
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