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CDKN2D Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P55273
Clone Names 100311229
Peptide ID 100311229
Additional Information
Gene ID 1032
Other Names Cyclin-dependent kinase 4 inhibitor D, p19-INK4d, CDKN2D
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Interacts strongly with CDK4 and CDK6 and inhibits them.
Cellular Location Nucleus. Cytoplasm
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the INK4family of cyclin-dependent kinase inhibitors. This protein has beenshown to form a stable complex with CDK4 or CDK6, and prevent theactivation of the CDK kinases, thus function as a cell growthregulator that controls cell cycle G1 progression. The abundance ofthe transcript of this gene was found to oscillate in a cell-cycledependent manner with the lowest expression at mid G1 and a maximalexpression during S phase. The negative regulation of the cellcycle involved in this protein was shown to participate inrepressing neuronal proliferation, as well as spermatogenesis. Twoalternatively spliced variants of this gene, which encode anidentical protein, have been reported.


Cunningham, J.M., et al. Br. J. Cancer 101(8):1461-1468(2009)Zhang, W., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41(5):414-428(2009)Agarwal, S.K., et al. J. Clin. Endocrinol. Metab. 94(5):1826-1834(2009)Goode, E.L., et al. Cancer Epidemiol. Biomarkers Prev. 18(3):935-944(2009)Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009)

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$ 80.00
Cat# BP16479c
Availability: In Stock
Bulk Size
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