|Other Names||Solute carrier organic anion transporter family member 2B1, Organic anion transporter B, OATP-B, Organic anion transporter polypeptide-related protein 2, OATP-RP2, OATPRP2, Solute carrier family 21 member 9, SLCO2B1, KIAA0880, OATP2B1, OATPB, SLC21A9|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA0880, OATP2B1, OATPB, SLC21A9|
|Function||Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Isoform 1 has it's highest expression in brain, it is the major form expressed in duodenum, kidney, placenta, and skeletal muscle. Isoform 3 predominates in liver|
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This locus encodes a member of the organicanion-transporting polypeptide family of membrane proteins. Theprotein encoded by this locus may function in regulation ofplacental uptake of sulfated steroids. Alternatively splicedtranscript variants have been described.
Man, M., et al. J Clin Pharmacol 50(8):929-940(2010)Justenhoven, C., et al. Breast Cancer Res. Treat. (2010) In press :Laitinen, A., et al. Basic Clin. Pharmacol. Toxicol. (2010) In press :Kock, K., et al. J. Biol. Chem. 285(15):11336-11347(2010)Hagenbuch, B., et al. Pflugers Arch. 447(5):653-665(2004)
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