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SLC25A30 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q5SVS4 |
|---|---|
| Clone Names | 100422133 |
| Gene ID | 253512 |
|---|---|
| Other Names | Kidney mitochondrial carrier protein 1, Solute carrier family 25 member 30, SLC25A30, KMCP1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SLC25A30 (HGNC:27371) |
|---|---|
| Function | Antiporter that transports inorganic anions (sulfate, sulfite, thiosulfate and phosphate) and, to a lesser extent, a variety of dicarboxylates (e.g. malonate, malate and citramalate) and, even more so, aspartate (PubMed:31356773). The sulfate/sulfate exchange is much higher than the phosphate/phosphate and malate/malate exchanges (PubMed:31356773). The transport affinities is higher for sulfate and thiosulfate than for any other substrate (PubMed:31356773). May catalyze the export of sulfite and thiosulfate (the hydrogen sulfide degradation products) from the mitochondria, thereby modulating the level of the hydrogen sulfide (Probable). Also may mediate a very low unidirectional transport of sulfate, phosphate and (S)-malate (PubMed:31356773). |
| Cellular Location | Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9CR58}; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Although the outer mitochondrial membrane is permeable tomany small metabolites, transport of solutes across the innermitochondrial membrane is achieved by members of the mitochondrialcarrier protein family, such as SLC25A30 (Haguenauer et al., 2005[PubMed 15809292]).
References
Haguenauer, A., et al. J. Biol. Chem. 280(23):22036-22043(2005)
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