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ELOVL7 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession A1L3X0
Clone Names 100422225
Peptide ID 100422225
Additional Information
Gene ID 79993
Other Names Elongation of very long chain fatty acids protein 7, 3-keto acyl-CoA synthase ELOVL7, ELOVL fatty acid elongase 7, ELOVL FA elongase 7, Very-long-chain 3-oxoacyl-CoA synthase 7, ELOVL7
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ELOVL7 {ECO:0000255|HAMAP-Rule:MF_03207}
Function Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate in the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Cellular Location Endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_03207, ECO:0000269|PubMed:20937905}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03207}
Tissue Location Expressed in most tissues except heart and skeletal muscle.
Research Areas
Citations (0)

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Background

ELOVL7 could be implicated in synthesis of very long chain fatty acids and sphingolipids (By similarity).

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Tamura, K., et al. Cancer Res. 69(20):8133-8140(2009)Lehner, R., et al. Prog. Lipid Res. 35(2):169-201(1996)

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$ 80.00
Cat# BP16487b
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