|Other Names||Fos-related antigen 2, FRA-2, FOSL2, FRA2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Controls osteoclast survival and size. As a dimer with JUN, activates LIF transcription. Activates CEBPB transcription in PGE2-activated osteoblasts.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The Fos gene family consists of 4 members: FOS, FOSB,FOSL1, and FOSL2. These genes encode leucine zipper proteins thatcan dimerize with proteins of the JUN family, thereby forming thetranscription factor complex AP-1. As such, the FOS proteins havebeen implicated as regulators of cell proliferation,differentiation, and transformation.
Bozec, A., et al. J. Cell Biol. 190(6):1093-1106(2010)Bolat, I., et al. Folia Histochem. Cytobiol. 48(2):197-201(2010)Reich, N., et al. Arthritis Rheum. 62(1):280-290(2010)Maurer, B., et al. Circulation 120(23):2367-2376(2009)Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.