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ADI1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BV57
Clone Names 100528278
Peptide ID 100528278
Additional Information
Gene ID 55256
Other Names 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}, 1131154 {ECO:0000255|HAMAP-Rule:MF_03154}, Acireductone dioxygenase (Fe(2+)-requiring) {ECO:0000255|HAMAP-Rule:MF_03154}, ARD {ECO:0000255|HAMAP-Rule:MF_03154}, Fe-ARD {ECO:0000255|HAMAP-Rule:MF_03154}, Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_03154}, MTCBP-1 {ECO:0000255|HAMAP-Rule:MF_03154}, Submergence-induced protein-like factor, Sip-L, ADI1 {ECO:0000255|HAMAP-Rule:MF_03154}
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADI1 {ECO:0000255|HAMAP-Rule:MF_03154}
Function Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.
Cellular Location Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the plasma membrane when complexed to MMP14
Tissue Location Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney
Research Areas
Citations (0)

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This gene encodes an enzyme that belongs to theaci-reductone dioxygenase family of metal-binding enzymes, whichare involved in methionine salvage. This enzyme may regulate mRNAprocessing in the nucleus, and may carry out different functionsdepending on its localization. Related pseudogenes have beendefined on chromosomes 8 and 20.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Cheng, J.C., et al. J. Med. Virol. 81(9):1560-1568(2009)Oram, S.W., et al. Neoplasia 9(8):643-651(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Gotoh, I., et al. Genes Cells 12(1):105-117(2007)

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$ 80.00
Cat# BP16495c
Availability: In Stock
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